Merete Fredholm

Merete Fredholm

Professor


  1. Published

    Ascaris suum infection down-regulates inflammatory pathways in the pig intestine in vivo and in human dendritic cells in vitro

    Midttun, H. L. E., Acevedo, N., Skallerup, P., Almeida, Sara dos Santos, Skovgaard, K., Andresen, Lars, Skov, Søren, Caraballo, L., van Die, I., Jørgensen, Claus Bøttcher, Fredholm, Merete, Thamsborg, Stig Milan, Nejsum, P. & Williams, Andrew Richard, 2018, In: The Journal of Infectious Diseases. 217, 2, p. 310-319

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Breeding for parasite resistance in pigs - a future option?

    Nejsum, P., Roepstorff, A. K., Jørgensen, Claus Bøttcher, Fredholm, Merete & Thamsborg, Stig Milan, 2006, Proceedings of the 19th IPVS Congress. Vol. 2. p. 410 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  3. Published

    A Gly98Val mutation in the N-myc downstream regulated gene 1 (NDRG1) in Alaskan Malamutes with polyneuropathy

    Bruun, C. V. S., Jäderlund, K. H., Berendt, M., Jensen, K. B., Spodsberg, E-M. H., Gredal, H. B., Shelton, G. D., Mickelson, J. R., Minor, K. M., Lohi, H., Bjerkås, I., Stigen, Ø., Espenes, A., Rohdin, C., Edlund, R., Ohlsson, J., Cizinauskas, S., Leifsson, P. S., Drögemüller, C., Moe, L. & 2 others, Cirera, Susanna & Fredholm, Merete, 2013, In: PLOS one. 8, 2, p. 1-7 7 p., e54547.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A comprehensive linkage map of the pig based on a wild pig - Large White intercross

    Marklund, L., Johansson Moller, M., Høyheim, B., Davies, W., Fredholm, Merete, Juneja, R. K., Mariani, P., Coppieters, W., Ellegren, H. & Andersson, L., 1996, In: Animal Genetics. 27, p. 255-269 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A consensus linkage map for swine chromosome 7

    Rohrer, G. A., Alexander, L. J., Beattie, C. W., Wilkie, P., Flickinger, G. H., Schook, L. B., Paszek, A. A., Andersson, L., Mariani, P., Marklund, L., Fredholm, Merete, Hoyheim, B., Archibald, A. L., Nielsen, V. H., Milan, D. & Groenen, M. A. M., 1997, In: Animal Genetics. 28, p. 223-229 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A data resource of 838 porcine microsatellite sequences with repeat motifs of three to six bases

    Karlskov-Mortensen, Peter, Hu, Z. L., Reecy, J. M. & Fredholm, Merete, 2008, In: Animal Genetics. 39, 1, p. 85-86 2 p.

    Research output: Contribution to journalComment/debateResearch

  7. Published

    A deletion in the bovine FANCI gene compromises fertility by causing fetal death and brachyspina

    Charlier, C., Agerholm, Jørgen Steen, Coppieters, W., Karlskov-Mortensen, Peter, Li, W., Jong, G. D., Fasquelle, C., Karim, L., Cirera, Susanna, Gambisano, N., Ahariz, N., Mullaart, E., Georges, M. & Fredholm, Merete, 2012, In: PLoS ONE. 7, 8, 7 p., e43085.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A form of albinism in cattle is caused by a tyrosinase frameshift mutation

    Fredholm, Merete, Schmutz, S. M., Berryere, T. G., Ciobanu, D. C., Mileham, A. J. & Schmidtz, B. H., 2004, In: Mammalian Genome. 15, 1, p. 62-67 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A genetic marker test for brachyspina and fertility in cattle

    Georges, M., Coppieters, W., Charlier, C., Agerholm, Jørgen Steen & Fredholm, Merete, 2010, IPC No. C12Q 1/68 (2006.01), Patent No. WO 2010/012690 A1, 4 Feb 2010

    Research output: Patent

  10. Published

    A hereditary disposition for bovine peripheral nerve sheath tumors in Danish Holstein cattle

    Grossi, A. B., Agerholm, Jørgen Steen, Christensen, Knud Arnbjerg, Jensen, Henrik Elvang, Leifsson, Páll S., Bendixen, C., Karlskov-Mortensen, Peter & Fredholm, Merete, 2014, In: Acta Veterinaria Scandinavica (Online). 56, 6 p., 85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A high-fat, low-fibre diet affects gastrointestinal growth, function and microbiology in aged pigs

    Sangild, Per Torp, Thymann, Thomas, Cirera, Susanna, Fredholm, Merete, Caribe, N. & Olsen, J., 2006, Proceedings from LMC International Food Congress 2006. Taylor, p. 31 1 p. (Scandinavian Journal of Food and Nutrition, Vol. 50, Suppl. 1).

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  12. Published

    A high-resolution comparative map between pig chromosome 17 and human chromosomes 4, 8, and 20: Identification of synteny breakpoints

    Lahbib-Mansais, Y., Karlskov-Mortensen, Peter, Mompart, F., Milan, D., Jørgensen, Claus Bøttcher, Cirera, Susanna, Gorodkin, Jan, Faraut, T., Yerle, M. & Fredholm, Merete, 2005, In: Genomics. 86, 4, p. 405-413 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A large insertion in intron 2 of the TYRP1 gene associated with American Palomino phenotype in American mink

    Cirera, Susanna, Markakis, M. N., Kristensen, Thea, Vissenberg, K., Fredholm, Merete, Christensen, Knud Arnbjerg & Anistoroaei, R. M., Apr 2016, In: Mammalian Genome. 27, 3, p. 135-143 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A molecular study of congenital erythropoietic porphyria in cattle

    Agerholm, Jørgen Steen, Thulstrup, Peter Waaben, Bjerrum, Morten Jannik, Bendixen, C., Jørgensen, Claus Bøttcher & Fredholm, Merete, 2012, In: Animal Genetics. 43, 2, p. 210-215 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A novel technique for identification of Ascaris suum cohorts in pigs

    Nejsum, P., Thamsborg, Stig Milan, Jørgensen, Claus Bøttcher, Fredholm, Merete & Roepstorff, A. K., 2008, In: Veterinary Parasitology. 154, 1-2, p. 171-174 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A re-assigned American mink (Neovison vison) map optimal for genome-wide studies

    Anistoroaei, R. M., Nielsen, V. H., Markakis, M. N., Karlskov-Mortensen, Peter, Jørgensen, Claus Bøttcher, Christensen, Knud Arnbjerg & Fredholm, Merete, 2012, In: Gene. 511, 1, p. 66-72 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A search for association between production traits and marker genotypes on pig chromosome 4 in an inbred family

    Nissen, P. H., Christensen, Knud Arnbjerg, Jørgensen, Claus Bøttcher, Jørgensen, J. N. & Fredholm, Merete, 2001, In: Acta Agriculturae Scandinavica. Section A. Animal Science. 51, p. 161-166 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A study of alternative splicing in the pig

    Hillig, A. N., Cirera, Susanna, Gilchrist, M. J., Gorodkin, Jan, Jørgensen, Claus Bøttcher & Fredholm, Merete, 2010, In: BMC Research Notes. 3, 123, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A study of the occurrence of monochorionic and monozygotic twinning in the pig

    Bjerre, D., Thorup, F., Jørgensen, Claus Bøttcher, Vejlsted, M. & Fredholm, Merete, 2009, In: Animal Genetics. 40, 1, p. 53-56 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A systems genetics analysis of obesity using the Weighted Interaction SNP Hub (WISH) networks

    Kogelman, L., Fredholm, Merete & Kadarmideen, H., 2013.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  21. Published

    A targeted genotyping approach enhances identification of variants in taste receptor and appetite/reward genes of potential functional importance for obesity-related porcine traits

    Cirera, Susanna, Clop, A., Jacobsen, M. J., Guerin, M., Lesnik, P., Jørgensen, Claus Bøttcher, Fredholm, Merete & Karlskov-Mortensen, Peter, 2018, In: Animal Genetics. 49, 2, p. 110–118

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs

    Jacobsen, M. J., Havgaard, Jakob Hull, Mentzel, Caroline M. Junker, Sørensen, P. M., Pundhir, Sachin, Anthon, Christian, Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Jørgensen, Claus Bøttcher, Barrès, Romain & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement 4, p. 46-47 2 p., P2019.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Albinism in the american mink (Neovison vison) is associated with a tyrosinase nonsense mutation

    Anistoroaei, R. M., Fredholm, Merete, Christensen, Knud Arnbjerg & Leeb, T., 2008, In: Animal Genetics. 39, 6, p. 645-648 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity

    Jacobsen, M. J., Mentzel, Caroline M. Junker, Olesen, A. S., Huby, T., Jørgensen, Claus Bøttcher, Barrès, Romain, Fredholm, Merete & Simar, D., 2016, In: Journal of Diabetes Research. 2016, p. 1-11 8539057.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    An F2 pig resource population as a model for genetic studies of obesity and obesity-related diseases in humans: design and genetic parameters

    Kogelman, L., Kadarmideen, H., Mark, T., Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Jacobsen, M. J., Jørgensen, Claus Bøttcher & Fredholm, Merete, 2013, In: Frontiers in Genetics. 4, 14 p., 29.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    An integrative systems genetics approach reveals potential causal genes and pathways related to obesity

    Kogelman, L., Zhernakova, D. V., Westra, H., Cirera, Susanna, Fredholm, Merete, Franke, L. & Kadarmideen, H., 20 Oct 2015, In: Genome Medicine. 7, 15 p., 105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Analyses of pig genomes provide insight into porcine demography and evolution

    Groenen, M. A., Archibald, A. L., Uenishi, H., Tuggle, C. K., Takeuchi, Y., Rothschild, M. F., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H-J., Li, S., Larkin, D. M., Kim, H., Frantz, L. A. F., Caccamo, M., Ahn, H., Aken, B. L., Anselmo, A., Anthon, C., Auvil, L. & 116 others, Badaoui, B., Beattie, C. W., Bendixen, C., Berman, D., Blecha, F., Blomberg, J., Bolund, L., Bosse, M., Botti, S., Zhan, B., Bystrom, M., Capitanu, B., Carvalho-Silva, D., Chardon, P., Chen, C., Cheng, R., Choi, S., Chow, W., Clark, R. C., Clee, C., Crooijmans, R. P. M. A., Dawson, H. D., Dehais, P., Sapio, F. D., Dibbits, B., Drou, N., Du, Z., Eversole, K., Fadista, J., Fairley, S., Faraut, T., Faulkner, G. J., Fowler, K. E., Fredholm, Merete, Fritz, E., Gilbert, J. G. R., Giuffra, E., Gorodkin, Jan, Griffin, D. K., Harrow, J. L., Hayward, A., Howe, K., Hu, Z., Humphray, S. J., Hunt, T., Jensen, H. H., Jeon, J., Jern, P., Jones, M., Jurka, J., Kanamori, H., Kapetanovic, R., Kim, J., Kim, J., Kim, K., Kim, T., Larson, G., Lee, K., Lee, K., Leggett, R., Lewin, H. A., Li, Y., Liu, W., Loveland, J. E., Lu, Y., Lunney, J. K., Ma, J., Madsen, O., Mann, K., Matthews, L., McLaren, S., Morozumi, T., Murtaugh, M. P., Narayan, J., Nguyen, D. T., Ni, P., Oh, S., Onteru, S., Panitz, F., Park, E., Park, H., Pascal, G., Paudel, Y., Perez-Enciso, M., Ramirez-Gonzalez, R., Reecy, J. M., Rodriguez-Zas, S., Rohrer, G. A., Rund, L., Sang, Y., Schachtschneider, K., Schraiber, J. G., Schwartz, J., Scobie, L., Scott, C., Searle, S., Servin, B., Southey, B. R., Sperber, G., Stadler, P., Sweedler, J. V., Tafer, H., Thomsen, B., Wali, R., Wang, J., Wang, J., White, S., Xu, X., Yerke, M., Zhang, G., Zhang, J., Zhang, J., Zhao, S., Rogers, J., Churcher, C. & Schook, L. B., 2012, In: Nature. 491, 7424, p. 393-398 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Analysis of merged transcriptomic and genomic datasets to identify genes and pathways underlying residual feed intake in growing pigs

    Ibragimov, Emil, Pedersen, Anni Øyan, Xiao, L., Cirera, Susanna, Fredholm, Merete & Karlskov-Mortensen, Peter, 2022, In: Scientific Reports. 12, 21946.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Analysis of porcine body size variation using re-sequencing data of miniature and large pigs 06 Biological Sciences 0604 Genetics

    Reimer, C., Rubin, C. J., Sharifi, A. R., Ha, N. T., Weigend, S., Waldmann, K. H., Distl, O., Pant, S. D., Fredholm, Merete, Schlather, M. & Simianer, H., 2018, In: BMC Genomics. 19, 17 p., 687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Animal genome mapping projects

    Fredholm, Merete, 1996, In: Biotechnologia. 2, 33, p. 13-19 7 p.

    Research output: Contribution to journalJournal articleCommunication

  31. Published

    Arctic-adapted dogs emerged at the Pleistocene-Holocene transition

    Sinding, M. H. S., Gopalakrishnan, S., Ramos-Madrigal, J., de Manuel, M., Pitulko, V. V., Kuderna, L., Feuerborn, T. R., Frantz, L. A. F., Vieira, F. G., Niemann, J., Samaniego Castruita, J. A., Carøe, C., Andersen-Ranberg, E. U., Jordan, P. D., Pavlova, E. Y., Nikolskiy, P. A., Kasparov, A. K., Ivanova, V. V., Willerslev, E., Skoglund, P. & 15 others, Fredholm, Merete, Wennerberg, S. E., Heide-Jørgensen, M. P., Dietz, R., Sonne, C., Meldgaard, Morten, Dalén, L., Larson, G., Petersen, Bent, Sicheritz-Pontén, Thomas, Bachmann, L., Wiig, Ø., Marques-Bonet, T., Hansen, Anders Johannes & Gilbert, M Thomas P, 2020, In: Science (New York, N.Y.). 368, 6498, p. 1495-1499 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Assignment of transcripts to the porcine genome map by SSCP and somatic cell hybrid mapping

    Fridolfsson, A. K., Hori, T., Winterø, A. K., Fredholm, Merete, Yerle, M., Robic, A., Andersson, L. & Ellegren, H., 1996. 1 p.

    Research output: Contribution to conferencePosterResearch

  33. Published

    Association between the porcine Escherichia coli F18 receptor genotype and phenotype and susceptibility to colonisation and postweaning diarrhoea caused by E-coli O138:F18

    Frydendahl, K., Jensen, Tim Kåre, Andersen, J. S., Fredholm, Merete & Evans, G., 2003, In: Veterinary Microbiology. 93, 1, p. 39-51 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Association of fecal and serum microRNA profiles with gastrointestinal cancer and chronic inflammatory enteropathy in dogs

    Lyngby, Janne Graarup, Gòdia, M., Brogaard, L., Kristensen, Annemarie T., Fredholm, Merete, Skancke, E., Morris, J., Dupont, Nana, Salavati Schmitz, S., Argyle, D., Sánchez, A., Bjørnvad, Charlotte Reinhard, Cirera, Susanna & Nielsen, Lise Nikolic, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 1989-2001

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Association of serum and fecal microRNA profiles in cats with gastrointestinal cancer and chronic inflammatory enteropathy

    Brogaard, L., Lyngby, Janne Graarup, Kristensen, Annemarie T., Fredholm, Merete, Bjørnvad, Charlotte Reinhard, Salavati Schmitz, S., Skancke, E., Morris, J. S., Dupont, Nana, Argyle, D., Sánchez, A., Spohr, A., Graarup-Hansen, K., Nielsen, Lise Nikolic & Cirera, Susanna, 2023, In: Journal of Veterinary Internal Medicine. 37, 5, p. 1738-1749

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Association of serum and fecal microRNA profiles in healthy cats and cats with gastrointestinal cancer or chronic inflammatory enteropathy

    Lyngby, Janne Graarup, Brogaard, L., Kristensen, Annemarie T., Fredholm, Merete, Bjørnvad, Charlotte Reinhard, Salavati Schmitz, S., Skancke, E., Morris, J., Dupont, Nana, Argyle, D., Sánchez, S., Spohr, A., Graarup-Hansen, K., Nielsen, Lise Nikolic & Cirera, Susanna, 2024, In: Journal of Veterinary Internal Medicine. 38, 1, p. 741 1 p., ESCG-O-3.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  37. Published
  38. Published

    Beyond the sequenced swine genome: the swine transcriptome

    Fredholm, Merete, 2004. 4 p.

    Research output: Contribution to conferencePaperResearch

  39. Published

    Bioteknologi anvendt i avlen

    Fredholm, Merete, 1999. 3 p.

    Research output: Contribution to conferencePaperResearch

  40. Published

    Breed differences in natriuretic peptides in healthy dogs

    Sjöstrand, K., Wess, G., Ljungvall, I., Häggström, J., Merveille, A-C., Wiberg, M., Gouni, V., Willesen, J., Hanås, S., Lequarré, A-S., Sørensen, L. M., Wolf, J., Tiret, L., Kierczak, M., Forsberg, S., McEntee, K., Battaille, G., Seppälä, E., Lindblad-Toh, K., Georges, M. & 4 others, Lohi, H., Chetboul, V., Fredholm, Merete & Höglund, K., 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 451-457 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Breeding French bulldogs so that they breathe well-A long way to go

    Ravn-Mølby, E., Sindahl, L., Nielsen, Søren Saxmose, Bruun, Camilla Vibeke Sichlau, Sandøe, Peter & Fredholm, Merete, 2019, In: PLoS ONE. 14, 12, 14 p., e0226280.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Breeding schemes for intervertebral disc disease in dachshunds: Is disc calcification score preferable to genotyping of the FGF4 retrogene insertion on CFA12?

    Bruun, Camilla Vibeke Sichlau, Bruun, C., Marx, T., Proschowsky, Helle Friis & Fredholm, Merete, 2020, In: Canine medicine and genetics. 7, 18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Brug af DNA-markører: til at bestemme, om en hund tilhører en forbudt race

    Fredholm, Merete, Pedersen, L., Laursen, M. G. & Sandøe, Peter, 2018, In: Dansk Veterinaertidsskrift. 3, p. 26-28/ 3 p.

    Research output: Contribution to journalJournal articleResearch

  44. Published

    Characterisation of five candidate genes within the ETEC F4ab/ac candidate region in pigs

    Jacobsen, M. J., Cirera, Susanna, Joller, D., Esteso, G., Kracht, S. S., Edfors, I., Bendixen, C., Archibald, A. L., Vogeli, P., Neuenschwander, S., Bertschinger, H. U., Rampoldi, A., Andersson, L., Fredholm, Merete & Jørgensen, Claus Bøttcher, 2011, In: BMC Research Notes. 4, 225, 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published
  46. Published
  47. Published
  48. Published

    Characterization of phenotypically similar murine and porcine models of human lung emphysema

    Bruun, Camilla Vibeke Sichlau, Leifsson, Páll S., Jensen, Henrik Elvang, Johansen, L. K., Cirera, Susanna, Jørgensen, Claus Bøttcher, Nielsen, J. & Fredholm, Merete, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  49. Published

    Characterization of the genetic profile of five Danish dog breeds

    Pertoldi, C., Kristensen, T. N., Loeschcke, V., Berg, P., Praebel, A., Stronen, A. V., Proschowsky, Helle Friis & Fredholm, Merete, 2013, In: Journal of Animal Science. 91, 11, p. 5122-5127 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Characterization of the porcine carboxypeptidase E cDNA: comparative analysis and investigation of a non-synonymous SNP

    Hreidarsdôttir, G. E., Cirera, Susanna & Fredholm, Merete, 2007, In: Animal Biotechnology (Print Edition). 18, 1, p. 61-64 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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