Merete Fredholm
Professor
Animal Genetics, Bioinformatics and Breeding
Grønnegårdsvej 3, 1870 Frederiksberg C
Animal Welfare and Disease Control
Grønnegårdsvej 8
1870 Frederiksberg C
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Ascaris suum infection down-regulates inflammatory pathways in the pig intestine in vivo and in human dendritic cells in vitro
Midttun, H. L. E., Acevedo, N., Skallerup, P., Almeida, Sara dos Santos, Skovgaard, K., Andresen, Lars, Skov, Søren, Caraballo, L., van Die, I., Jørgensen, Claus Bøttcher, Fredholm, Merete, Thamsborg, Stig Milan, Nejsum, P. & Williams, Andrew Richard, 2018, In: The Journal of Infectious Diseases. 217, 2, p. 310-319Research output: Contribution to journal › Journal article › Research › peer-review
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Breeding for parasite resistance in pigs - a future option?
Nejsum, P., Roepstorff, A. K., Jørgensen, Claus Bøttcher, Fredholm, Merete & Thamsborg, Stig Milan, 2006, Proceedings of the 19th IPVS Congress. Vol. 2. p. 410 1 p.Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research
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A Gly98Val mutation in the N-myc downstream regulated gene 1 (NDRG1) in Alaskan Malamutes with polyneuropathy
Bruun, C. V. S., Jäderlund, K. H., Berendt, M., Jensen, K. B., Spodsberg, E-M. H., Gredal, H. B., Shelton, G. D., Mickelson, J. R., Minor, K. M., Lohi, H., Bjerkås, I., Stigen, Ø., Espenes, A., Rohdin, C., Edlund, R., Ohlsson, J., Cizinauskas, S., Leifsson, P. S., Drögemüller, C., Moe, L. & 2 others, , 2013, In: PLOS one. 8, 2, p. 1-7 7 p., e54547.Research output: Contribution to journal › Journal article › Research › peer-review
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A comprehensive linkage map of the pig based on a wild pig - Large White intercross
Marklund, L., Johansson Moller, M., Høyheim, B., Davies, W., Fredholm, Merete, Juneja, R. K., Mariani, P., Coppieters, W., Ellegren, H. & Andersson, L., 1996, In: Animal Genetics. 27, p. 255-269 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A consensus linkage map for swine chromosome 7
Rohrer, G. A., Alexander, L. J., Beattie, C. W., Wilkie, P., Flickinger, G. H., Schook, L. B., Paszek, A. A., Andersson, L., Mariani, P., Marklund, L., Fredholm, Merete, Hoyheim, B., Archibald, A. L., Nielsen, V. H., Milan, D. & Groenen, M. A. M., 1997, In: Animal Genetics. 28, p. 223-229 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A data resource of 838 porcine microsatellite sequences with repeat motifs of three to six bases
Karlskov-Mortensen, Peter, Hu, Z. L., Reecy, J. M. & Fredholm, Merete, 2008, In: Animal Genetics. 39, 1, p. 85-86 2 p.Research output: Contribution to journal › Comment/debate › Research
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A deletion in the bovine FANCI gene compromises fertility by causing fetal death and brachyspina
Charlier, C., Agerholm, Jørgen Steen, Coppieters, W., Karlskov-Mortensen, Peter, Li, W., Jong, G. D., Fasquelle, C., Karim, L., Cirera, Susanna, Gambisano, N., Ahariz, N., Mullaart, E., Georges, M. & Fredholm, Merete, 2012, In: PLoS ONE. 7, 8, 7 p., e43085.Research output: Contribution to journal › Journal article › Research › peer-review
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A form of albinism in cattle is caused by a tyrosinase frameshift mutation
Fredholm, Merete, Schmutz, S. M., Berryere, T. G., Ciobanu, D. C., Mileham, A. J. & Schmidtz, B. H., 2004, In: Mammalian Genome. 15, 1, p. 62-67 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A genetic marker test for brachyspina and fertility in cattle
Georges, M., Coppieters, W., Charlier, C., Agerholm, Jørgen Steen & Fredholm, Merete, 2010, IPC No. C12Q 1/68 (2006.01), Patent No. WO 2010/012690 A1, 4 Feb 2010Research output: Patent
- Published
A hereditary disposition for bovine peripheral nerve sheath tumors in Danish Holstein cattle
Grossi, A. B., Agerholm, Jørgen Steen, Christensen, Knud Arnbjerg, Jensen, Henrik Elvang, Leifsson, Páll S., Bendixen, C., Karlskov-Mortensen, Peter & Fredholm, Merete, 2014, In: Acta Veterinaria Scandinavica (Online). 56, 6 p., 85.Research output: Contribution to journal › Journal article › Research › peer-review
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A high-fat, low-fibre diet affects gastrointestinal growth, function and microbiology in aged pigs
Sangild, Per Torp, Thymann, Thomas, Cirera, Susanna, Fredholm, Merete, Caribe, N. & Olsen, J., 2006, Proceedings from LMC International Food Congress 2006. Taylor, p. 31 1 p. (Scandinavian Journal of Food and Nutrition, Vol. 50, Suppl. 1).Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research
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A high-resolution comparative map between pig chromosome 17 and human chromosomes 4, 8, and 20: Identification of synteny breakpoints
Lahbib-Mansais, Y., Karlskov-Mortensen, Peter, Mompart, F., Milan, D., Jørgensen, Claus Bøttcher, Cirera, Susanna, Gorodkin, Jan, Faraut, T., Yerle, M. & Fredholm, Merete, 2005, In: Genomics. 86, 4, p. 405-413 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A large insertion in intron 2 of the TYRP1 gene associated with American Palomino phenotype in American mink
Cirera, Susanna, Markakis, M. N., Kristensen, Thea, Vissenberg, K., Fredholm, Merete, Christensen, Knud Arnbjerg & Anistoroaei, R. M., Apr 2016, In: Mammalian Genome. 27, 3, p. 135-143 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A molecular study of congenital erythropoietic porphyria in cattle
Agerholm, Jørgen Steen, Thulstrup, Peter Waaben, Bjerrum, Morten Jannik, Bendixen, C., Jørgensen, Claus Bøttcher & Fredholm, Merete, 2012, In: Animal Genetics. 43, 2, p. 210-215 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A novel technique for identification of Ascaris suum cohorts in pigs
Nejsum, P., Thamsborg, Stig Milan, Jørgensen, Claus Bøttcher, Fredholm, Merete & Roepstorff, A. K., 2008, In: Veterinary Parasitology. 154, 1-2, p. 171-174 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A re-assigned American mink (Neovison vison) map optimal for genome-wide studies
Anistoroaei, R. M., Nielsen, V. H., Markakis, M. N., Karlskov-Mortensen, Peter, Jørgensen, Claus Bøttcher, Christensen, Knud Arnbjerg & Fredholm, Merete, 2012, In: Gene. 511, 1, p. 66-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A search for association between production traits and marker genotypes on pig chromosome 4 in an inbred family
Nissen, P. H., Christensen, Knud Arnbjerg, Jørgensen, Claus Bøttcher, Jørgensen, J. N. & Fredholm, Merete, 2001, In: Acta Agriculturae Scandinavica. Section A. Animal Science. 51, p. 161-166 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A study of alternative splicing in the pig
Hillig, A. N., Cirera, Susanna, Gilchrist, M. J., Gorodkin, Jan, Jørgensen, Claus Bøttcher & Fredholm, Merete, 2010, In: BMC Research Notes. 3, 123, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A study of the occurrence of monochorionic and monozygotic twinning in the pig
Bjerre, D., Thorup, F., Jørgensen, Claus Bøttcher, Vejlsted, M. & Fredholm, Merete, 2009, In: Animal Genetics. 40, 1, p. 53-56 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A systems genetics analysis of obesity using the Weighted Interaction SNP Hub (WISH) networks
Kogelman, L., Fredholm, Merete & Kadarmideen, H., 2013.Research output: Contribution to conference › Conference abstract for conference › Research
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A targeted genotyping approach enhances identification of variants in taste receptor and appetite/reward genes of potential functional importance for obesity-related porcine traits
Cirera, Susanna, Clop, A., Jacobsen, M. J., Guerin, M., Lesnik, P., Jørgensen, Claus Bøttcher, Fredholm, Merete & Karlskov-Mortensen, Peter, 2018, In: Animal Genetics. 49, 2, p. 110–118Research output: Contribution to journal › Journal article › Research › peer-review
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Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs
Jacobsen, M. J., Havgaard, Jakob Hull, Mentzel, Caroline M. Junker, Sørensen, P. M., Pundhir, Sachin, Anthon, Christian, Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Jørgensen, Claus Bøttcher, Barrès, Romain & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement 4, p. 46-47 2 p., P2019.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Albinism in the american mink (Neovison vison) is associated with a tyrosinase nonsense mutation
Anistoroaei, R. M., Fredholm, Merete, Christensen, Knud Arnbjerg & Leeb, T., 2008, In: Animal Genetics. 39, 6, p. 645-648 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity
Jacobsen, M. J., Mentzel, Caroline M. Junker, Olesen, A. S., Huby, T., Jørgensen, Claus Bøttcher, Barrès, Romain, Fredholm, Merete & Simar, D., 2016, In: Journal of Diabetes Research. 2016, p. 1-11 8539057.Research output: Contribution to journal › Journal article › Research › peer-review
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An F2 pig resource population as a model for genetic studies of obesity and obesity-related diseases in humans: design and genetic parameters
Kogelman, L., Kadarmideen, H., Mark, T., Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Jacobsen, M. J., Jørgensen, Claus Bøttcher & Fredholm, Merete, 2013, In: Frontiers in Genetics. 4, 14 p., 29.Research output: Contribution to journal › Journal article › Research › peer-review
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An integrative systems genetics approach reveals potential causal genes and pathways related to obesity
Kogelman, L., Zhernakova, D. V., Westra, H., Cirera, Susanna, Fredholm, Merete, Franke, L. & Kadarmideen, H., 20 Oct 2015, In: Genome Medicine. 7, 15 p., 105.Research output: Contribution to journal › Journal article › Research › peer-review
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Analyses of pig genomes provide insight into porcine demography and evolution
Groenen, M. A., Archibald, A. L., Uenishi, H., Tuggle, C. K., Takeuchi, Y., Rothschild, M. F., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H-J., Li, S., Larkin, D. M., Kim, H., Frantz, L. A. F., Caccamo, M., Ahn, H., Aken, B. L., Anselmo, A., Anthon, C., Auvil, L. & 116 others, , 2012, In: Nature. 491, 7424, p. 393-398 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of merged transcriptomic and genomic datasets to identify genes and pathways underlying residual feed intake in growing pigs
Ibragimov, Emil, Pedersen, Anni Øyan, Xiao, L., Cirera, Susanna, Fredholm, Merete & Karlskov-Mortensen, Peter, 2022, In: Scientific Reports. 12, 21946.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of porcine body size variation using re-sequencing data of miniature and large pigs 06 Biological Sciences 0604 Genetics
Reimer, C., Rubin, C. J., Sharifi, A. R., Ha, N. T., Weigend, S., Waldmann, K. H., Distl, O., Pant, S. D., Fredholm, Merete, Schlather, M. & Simianer, H., 2018, In: BMC Genomics. 19, 17 p., 687.Research output: Contribution to journal › Journal article › Research › peer-review
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Animal genome mapping projects
Fredholm, Merete, 1996, In: Biotechnologia. 2, 33, p. 13-19 7 p.Research output: Contribution to journal › Journal article › Communication
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Arctic-adapted dogs emerged at the Pleistocene-Holocene transition
Sinding, M. H. S., Gopalakrishnan, S., Ramos-Madrigal, J., de Manuel, M., Pitulko, V. V., Kuderna, L., Feuerborn, T. R., Frantz, L. A. F., Vieira, F. G., Niemann, J., Samaniego Castruita, J. A., Carøe, C., Andersen-Ranberg, E. U., Jordan, P. D., Pavlova, E. Y., Nikolskiy, P. A., Kasparov, A. K., Ivanova, V. V., Willerslev, E., Skoglund, P. & 15 others, , 2020, In: Science (New York, N.Y.). 368, 6498, p. 1495-1499 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assignment of transcripts to the porcine genome map by SSCP and somatic cell hybrid mapping
Fridolfsson, A. K., Hori, T., Winterø, A. K., Fredholm, Merete, Yerle, M., Robic, A., Andersson, L. & Ellegren, H., 1996. 1 p.Research output: Contribution to conference › Poster › Research
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Association between the porcine Escherichia coli F18 receptor genotype and phenotype and susceptibility to colonisation and postweaning diarrhoea caused by E-coli O138:F18
Frydendahl, K., Jensen, Tim Kåre, Andersen, J. S., Fredholm, Merete & Evans, G., 2003, In: Veterinary Microbiology. 93, 1, p. 39-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of fecal and serum microRNA profiles with gastrointestinal cancer and chronic inflammatory enteropathy in dogs
Lyngby, Janne Graarup, Gòdia, M., Brogaard, L., Kristensen, Annemarie T., Fredholm, Merete, Skancke, E., Morris, J., Dupont, Nana, Salavati Schmitz, S., Argyle, D., Sánchez, A., Bjørnvad, Charlotte Reinhard, Cirera, Susanna & Nielsen, Lise Nikolic, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 1989-2001Research output: Contribution to journal › Journal article › Research › peer-review
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Association of serum and fecal microRNA profiles in cats with gastrointestinal cancer and chronic inflammatory enteropathy
Brogaard, L., Lyngby, Janne Graarup, Kristensen, Annemarie T., Fredholm, Merete, Bjørnvad, Charlotte Reinhard, Salavati Schmitz, S., Skancke, E., Morris, J. S., Dupont, Nana, Argyle, D., Sánchez, A., Spohr, A., Graarup-Hansen, K., Nielsen, Lise Nikolic & Cirera, Susanna, 2023, In: Journal of Veterinary Internal Medicine. 37, 5, p. 1738-1749Research output: Contribution to journal › Journal article › Research › peer-review
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Association of serum and fecal microRNA profiles in healthy cats and cats with gastrointestinal cancer or chronic inflammatory enteropathy
Lyngby, Janne Graarup, Brogaard, L., Kristensen, Annemarie T., Fredholm, Merete, Bjørnvad, Charlotte Reinhard, Salavati Schmitz, S., Skancke, E., Morris, J., Dupont, Nana, Argyle, D., Sánchez, S., Spohr, A., Graarup-Hansen, K., Nielsen, Lise Nikolic & Cirera, Susanna, 2024, In: Journal of Veterinary Internal Medicine. 38, 1, p. 741 1 p., ESCG-O-3.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Beyond the sequenced swine genome: the swine transcriptome
Fredholm, Merete, 2004. 4 p.Research output: Contribution to conference › Paper › Research
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Bioteknologi anvendt i avlen
Fredholm, Merete, 1999. 3 p.Research output: Contribution to conference › Paper › Research
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Breed differences in natriuretic peptides in healthy dogs
Sjöstrand, K., Wess, G., Ljungvall, I., Häggström, J., Merveille, A-C., Wiberg, M., Gouni, V., Willesen, J., Hanås, S., Lequarré, A-S., Sørensen, L. M., Wolf, J., Tiret, L., Kierczak, M., Forsberg, S., McEntee, K., Battaille, G., Seppälä, E., Lindblad-Toh, K., Georges, M. & 4 others, , 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 451-457 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Breeding French bulldogs so that they breathe well-A long way to go
Ravn-Mølby, E., Sindahl, L., Nielsen, Søren Saxmose, Bruun, Camilla Vibeke Sichlau, Sandøe, Peter & Fredholm, Merete, 2019, In: PLoS ONE. 14, 12, 14 p., e0226280.Research output: Contribution to journal › Journal article › Research › peer-review
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Breeding schemes for intervertebral disc disease in dachshunds: Is disc calcification score preferable to genotyping of the FGF4 retrogene insertion on CFA12?
Bruun, Camilla Vibeke Sichlau, Bruun, C., Marx, T., Proschowsky, Helle Friis & Fredholm, Merete, 2020, In: Canine medicine and genetics. 7, 18.Research output: Contribution to journal › Journal article › Research › peer-review
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Brug af DNA-markører: til at bestemme, om en hund tilhører en forbudt race
Fredholm, Merete, Pedersen, L., Laursen, M. G. & Sandøe, Peter, 2018, In: Dansk Veterinaertidsskrift. 3, p. 26-28/ 3 p.Research output: Contribution to journal › Journal article › Research
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Characterisation of five candidate genes within the ETEC F4ab/ac candidate region in pigs
Jacobsen, M. J., Cirera, Susanna, Joller, D., Esteso, G., Kracht, S. S., Edfors, I., Bendixen, C., Archibald, A. L., Vogeli, P., Neuenschwander, S., Bertschinger, H. U., Rampoldi, A., Andersson, L., Fredholm, Merete & Jørgensen, Claus Bøttcher, 2011, In: BMC Research Notes. 4, 225, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of phenotypically similar murine and porcine models of human lung emphysema
Fredholm, Merete, Bruun, Camilla Vibeke Sichlau, Leifsson, Páll S., Jensen, Henrik Elvang, Jensen, Louise Kruse, Cirera, Susanna, Jørgensen, Claus Bøttcher & Nielsen, J., 2009. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Characterization of phenotypically similar murine and porcine models of human lung emphysema
Bruun, Camilla Vibeke Sichlau, Leifsson, Páll S., Jensen, Henrik Elvang, Jensen, Louise Kruse, Cirera, Susanna, Jørgensen, Claus Bøttcher, Nielsen, J. & Fredholm, Merete, 2009. 1 p.Research output: Contribution to conference › Poster › Research
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Characterization of phenotypically similar murine and porcine models of human lung emphysema
Bruun, Camilla Vibeke Sichlau, Leifsson, Páll S., Jensen, Henrik Elvang, Jensen, Louise Kruse, Cirera, Susanna, Jørgensen, Claus Bøttcher, Nielsen, J. & Fredholm, Merete, 2009. 1 p.Research output: Contribution to conference › Poster › Research
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Characterization of phenotypically similar murine and porcine models of human lung emphysema
Bruun, Camilla Vibeke Sichlau, Leifsson, Páll S., Jensen, Henrik Elvang, Johansen, L. K., Cirera, Susanna, Jørgensen, Claus Bøttcher, Nielsen, J. & Fredholm, Merete, 2009. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Characterization of the genetic profile of five Danish dog breeds
Pertoldi, C., Kristensen, T. N., Loeschcke, V., Berg, P., Praebel, A., Stronen, A. V., Proschowsky, Helle Friis & Fredholm, Merete, 2013, In: Journal of Animal Science. 91, 11, p. 5122-5127 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the porcine carboxypeptidase E cDNA: comparative analysis and investigation of a non-synonymous SNP
Hreidarsdôttir, G. E., Cirera, Susanna & Fredholm, Merete, 2007, In: Animal Biotechnology (Print Edition). 18, 1, p. 61-64 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4229506
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Selektiv avl af racehunde og -katte: kan den ske på en velfærdsmæssigt forsvarlig måde?
Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
Research output: Contribution to journal › Journal article › Research › peer-review
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Avl for forbedret velfærd hos racehunde
Research output: Contribution to conference › Poster › Research
Published