Merete Fredholm

Association of serum and fecal microRNA profiles in healthy cats and cats with gastrointestinal cancer or chronic inflammatory enteropathy

Lyngby, Janne Graarup, Brogaard, L., Kristensen, Annemarie T., Fredholm, Merete, Bjørnvad, Charlotte Reinhard, Salavati Schmitz, S., Skancke, E., Morris, J., Dupont, Nana, Argyle, D., Sánchez, S., Spohr, A., Graarup-Hansen, K., Nielsen, Lise Nikolic & Cirera, Susanna, 2024, In: Journal of Veterinary Internal Medicine. 38, 1, p. 741 1 p., ESCG-O-3.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Mitral valve transcriptome analysis in thirty-four age-matched Cavalier King Charles Spaniels with or without congestive heart failure caused by myxomatous mitral valve disease

Reimann, Maria Josefine, Cremer, Signe Emilie, Christiansen, L., Ibragimov, Emil, Gao, Fei, Cirera, Susanna, Fredholm, Merete, Olsen, Lisbeth Høier & Karlskov-Mortensen, Peter, 2024, In: Mammalian Genome. 35, 1, p. 77-89 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs

Zeng, H., Zhang, W., Lin, Q., Gao, Y., Teng, J., Xu, Z., Cai, X., Zhong, Z., Wu, J., Liu, Y., Diao, S., Wei, C., Gong, W., Pan, X., Li, Z., Huang, X., Chen, X., Du, J., Zhao, F., Zhao, Y. & 19 others, Ballester, M., Crespo-Piazuelo, D., Amills, M., Clop, A., Karlskov-Mortensen, Peter, Fredholm, Merete, Li, P., Huang, R., Tang, G., Li, M., Liu, X., Chen, Y., Zhang, Q., Li, J., Yuan, X., Ding, X., Fang, L., Zhang, Z. & The PigGTEx Consortium, T. P. C., 2024, In: Nucleic Acids Research. 52, D1, p. D980-D989 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Relationship between syringomyelia and myxomatous mitral valve disease in Cavalier King Charles spaniels

Bach, Maiken Bayer Thode, Stougaard, C. L., Thøfner, M. S., Reimann, Maria Josefine, Westrup, U., Koch, Jørgen, Fredholm, Merete, Martinussen, Torben, Berendt, Mette & Olsen, Lisbeth Høier, 2024, In: Journal of Veterinary Internal Medicine. 38, 2, p. 904-912 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Towards identification of new genetic determinants for post-weaning diarrhea in piglets

Ibragimov, Emil, Eriksen, E. Ø., Nielsen, Jens Peter, Jørgensen, Claus Bøttcher, Fredholm, Merete & Karlskov-Mortensen, Peter, 2024, (E-pub ahead of print) In: Animal Genetics. 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of serum and fecal microRNA profiles in cats with gastrointestinal cancer and chronic inflammatory enteropathy

Brogaard, L., Lyngby, Janne Graarup, Kristensen, Annemarie T., Fredholm, Merete, Bjørnvad, Charlotte Reinhard, Salavati Schmitz, S., Skancke, E., Morris, J. S., Dupont, Nana, Argyle, D., Sánchez, A., Spohr, A., Graarup-Hansen, K., Nielsen, Lise Nikolic & Cirera, Susanna, 2023, In: Journal of Veterinary Internal Medicine. 37, 5, p. 1738-1749

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluation of the value of genetic testing for cystinuria in the Danish population of English bulldogs

Fitzwilliams, Therese Emilie Glar, Wolff-Sneedorff, J. L., Fredholm, Merete, Karlskov-Mortensen, Peter, Guldbrandtsen, Bernt & Bruun, Camilla Vibeke Sichlau, 2023, In: Animal Genetics. 54, 4, p. 566-569

Research output: Contribution to journal › Journal article › Research › peer-review

Kortlægning af initiativer til at modvirke usund avl

Bruun, Camilla Vibeke Sichlau, Fredholm, Merete, Proschowsky, Helle Friis & Sandøe, Peter, 2023, In: Dansk Veterinaertidsskrift. 2023, 11, p. 18-22 5 p.

Research output: Contribution to journal › Journal article › Research

Analysis of merged transcriptomic and genomic datasets to identify genes and pathways underlying residual feed intake in growing pigs

Ibragimov, Emil, Pedersen, Anni Øyan, Xiao, L., Cirera, Susanna, Fredholm, Merete & Karlskov-Mortensen, Peter, 2022, In: Scientific Reports. 12, 21946.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of fecal and serum microRNA profiles with gastrointestinal cancer and chronic inflammatory enteropathy in dogs

Lyngby, Janne Graarup, Gòdia, M., Brogaard, L., Kristensen, Annemarie T., Fredholm, Merete, Skancke, E., Morris, J., Dupont, Nana, Salavati Schmitz, S., Argyle, D., Sánchez, A., Bjørnvad, Charlotte Reinhard, Cirera, Susanna & Nielsen, Lise Nikolic, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 1989-2001

Research output: Contribution to journal › Journal article › Research › peer-review

Modeling microRNA-driven post-transcriptional regulation using exon–intron split analysis in pigs

Mármol-Sánchez, E., Cirera, Susanna, Zingaretti, L. M., Jacobsen, M. J., Ramayo-Caldas, Y., Jørgensen, Claus Bøttcher, Fredholm, Merete, Cardoso, T. F., Quintanilla, R. & Amills, M., 2022, In: Animal Genetics. 53, 5, p. 613-626

Research output: Contribution to journal › Journal article › Research › peer-review

Pampered pets or poor bastards? The welfare of dogs kept as companion animals

Meyer, Iben, Forkman, Björn, Fredholm, Merete, Glanville, C., Guldbrandtsen, Bernt, Ruiz Izaguirre, E., Palmer, C. & Sandøe, Peter, 2022, In: Applied Animal Behaviour Science. 251, 105640.

Research output: Contribution to journal › Journal article › Research › peer-review

Diet-Dependent Changes of the DNA Methylome Using a Göttingen Minipig Model for Obesity

Feng, Y., Cirera, Susanna, Taşöz, E., Liu, Y., Olsen, Lisbeth Høier, Christoffersen, B. Ø., Pedersen, H. D., Ludvigsen, T. P., Kirk, R. K., Schumacher-Petersen, Camilla, Deng, Y., Fredholm, Merete & Gao, Fei, 2021, In: Frontiers in Genetics. 12, 632859.

Research output: Contribution to journal › Journal article › Research › peer-review

Exercise-Associated Sudden Death in Finnish Standardbred and Coldblooded Trotters - A Case Series With Pedigree Analysis

Trachsel, D. S., Callø, Kirstine, Mykkänen, A. K., Raistakka, P., Anttila, M., Fredholm, Merete, Tala, M., Lamminpää, K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: Journal of Equine Veterinary Science. 104, 103694.

Research output: Contribution to journal › Journal article › Research › peer-review

Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D

Skedsmo, F. S., Espenes, A., Tranulis, M. A., Matiasek, K., Gunnes, G., Bjerkås, I., Moe, L., Røed, S. S., Berendt, Mette, Fredholm, Merete, Rohdin, C., Shelton, G. D., Bruheim, P., Stafsnes, M. H., Bartosova, Z., Hermansen, L. C., Stigen, Ø. & Jäderlund, K. H., 2021, In: Neuromuscular Disorders. 31, 1, p. 56-68

Research output: Contribution to journal › Journal article › Research › peer-review

Kan vi bruge den nye DNA-test for diskusprolaps?

Bruun, Camilla Vibeke Sichlau & Fredholm, Merete, 2021, In: Gravhunden. 2021, 3, p. 29-31 3 p.

Research output: Contribution to journal › Journal article › Communication

Pig genome functional annotation enhances the biological interpretation of complex traits and human disease

Pan, Z., Yao, Y., Yin, H., Cai, Z., Wang, Y., Bai, L., Kern, C., Halstead, M., Chanthavixay, G., Trakooljul, N., Wimmers, K., Sahana, G., Su, G., Lund, M. S., Fredholm, M., Karlskov-Mortensen, P., Ernst, C. W., Ross, P., Tuggle, C. K., Fang, L. & 1 others, Zhou, H., 2021, In: Nature Communications. 12, 1, 5848.

Research output: Contribution to journal › Journal article › Research › peer-review

Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606

Research output: Contribution to journal › Journal article › Research › peer-review

Stor andel af Labrador retrievere i Danmark bærer den nedarvede øjensygdom Stargardt disease

Mørch, A., Panholm, L., Ysbæk-Nielsen, K., Knudsen, J. K., Sandøe, Peter & Fredholm, Merete, 2021, In: Dansk Veterinærtidsskrift. 2021, 7, p. 25-27 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The first genome-wide association study concerning idiopathic epilepsy in Petit Basset Griffon Vendeen

Deschain, T., Fabricius, J., Berendt, Mette, Fredholm, Merete & Karlskov-Mortensen, Peter, 2021, In: Animal Genetics. 52, 5, p. 762-766

Research output: Contribution to journal › Journal article › Research › peer-review

Unraveling molecular mechanisms involved in the development of leptin resistance using the pig as a model

Mármol-Sánchez, E., Artman, J. S., Fredholm, Merete & Cirera, Susanna, 2021, In: Animal Genetics. 52, 1, p. 55-65

Research output: Contribution to journal › Journal article › Research › peer-review

Arctic-adapted dogs emerged at the Pleistocene-Holocene transition

Sinding, M. H. S., Gopalakrishnan, S., Ramos-Madrigal, J., de Manuel, M., Pitulko, V. V., Kuderna, L., Feuerborn, T. R., Frantz, L. A. F., Vieira, F. G., Niemann, J., Samaniego Castruita, J. A., Carøe, C., Andersen-Ranberg, E. U., Jordan, P. D., Pavlova, E. Y., Nikolskiy, P. A., Kasparov, A. K., Ivanova, V. V., Willerslev, E., Skoglund, P. & 15 others, Fredholm, Merete, Wennerberg, S. E., Heide-Jørgensen, M. P., Dietz, R., Sonne, C., Meldgaard, Morten, Dalén, L., Larson, G., Petersen, Bent, Sicheritz-Pontén, Thomas, Bachmann, L., Wiig, Ø., Marques-Bonet, T., Hansen, Anders Johannes & Gilbert, M Thomas P, 2020, In: Science (New York, N.Y.). 368, 6498, p. 1495-1499 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Breeding schemes for intervertebral disc disease in dachshunds: Is disc calcification score preferable to genotyping of the FGF4 retrogene insertion on CFA12?

Bruun, Camilla Vibeke Sichlau, Bruun, C., Marx, T., Proschowsky, Helle Friis & Fredholm, Merete, 2020, In: Canine medicine and genetics. 7, 18.

Research output: Contribution to journal › Journal article › Research › peer-review

Fgf21 regulates hepatic metabolic pathways to improve steatosis and inflammation

Keinicke, H., Sun, G., Mentzel, Caroline M. Junker, Fredholm, Merete, John, L. M., Andersen, B., Raun, K. & Kjaergaard, M., 2020, In: Endocrine Connections. 9, 8, p. 755-768 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome wide association study of 40 clinical measurements in eight dog breeds

Momozawa, Y., Merveille, A. C., Battaille, G., Wiberg, M., Koch, Jørgen, Willesen, Jakob, Proschowsky, Helle Friis, Gouni, V., Chetboul, V., Tiret, L., Fredholm, Merete, Seppälä, E. H., Lohi, H., Georges, M. & Lequarré, A. S., 2020, In: Scientific Reports. 10, 6520.

Research output: Contribution to journal › Journal article › Research › peer-review

Genomic diversity revealed by whole-genome sequencing in three Danish commercial pig breeds

Cai, Z., Sarup, P., Ostersen, T., Nielsen, B., Fredholm, Merete, Karlskov-Mortensen, Peter, Sørensen, P., Jensen, J., Guldbrandtsen, B., Lund, M. S., Christensen, Ole Fredslund Borg & Sahana, G., 2020, In: Journal of Animal Science. 98, 7, skaa229.

Research output: Contribution to journal › Journal article › Research › peer-review

Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels

Zhang, Q., Cai, Z., Lhomme, M., Sahana, G., Lesnik, P., Guerin, M., Fredholm, Merete & Karlskov-Mortensen, Peter, 2020, In: Scientific Reports. 10, 1, 14 p., 18434.

Research output: Contribution to journal › Journal article › Research › peer-review

NASH-inducing Diets in Göttingen Minipigs

Pedersen, H. D., Galsgaard, E. D., Christoffersen, B., Cirera, Susanna, Holst, D., Fredholm, Merete & Latta, M., 2020, In: Journal of Clinical and Experimental Hepatology. 10, 3, p. 211-221

Research output: Contribution to journal › Journal article › Research › peer-review

The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation

Cirera, Susanna, Taşöz, E., Juul Jacobsen, M., Schumacher-Petersen, Camilla, Østergaard Christoffersen, B., Kaae Kirk, R., Pagh Ludvigsen, T., Hvid, H., Duelund Pedersen, H., Olsen, Lisbeth Høier & Fredholm, Merete, 2020, In: Nutrition and Diabetes. 10, 1, 12 p., 9.

Research output: Contribution to journal › Journal article › Research › peer-review

Validation of DNA test for hip dysplasia failed in Danish Labrador Retrievers

Bruun, Camilla Vibeke Sichlau, Bank, A., Ström, A., Proschowsky, Helle Friis & Fredholm, Merete, 2020, In: Animal Genetics. 51, 4, p. 617-619

Research output: Contribution to journal › Journal article › Research › peer-review

Breeding French bulldogs so that they breathe well-A long way to go

Ravn-Mølby, E., Sindahl, L., Nielsen, Søren Saxmose, Bruun, Camilla Vibeke Sichlau, Sandøe, Peter & Fredholm, Merete, 2019, In: PLoS ONE. 14, 12, 14 p., e0226280.

Research output: Contribution to journal › Journal article › Research › peer-review

Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism

Jacobsen, M. J., Havgaard, Jakob Hull, Anthon, Christian, Mentzel, Caroline M. Junker, Cirera, Susanna, Krogh, P. M., Pundhir, Sachin, Karlskov-Mortensen, Peter, Bruun, C. S., Lesnik, P., Guerin, M., Gorodkin, Jan, Jørgensen, Claus Bøttcher, Fredholm, Merete & Barrès, Romain, 2019, In: Frontiers in Genetics. 10, 13 p., 1268.

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluation of fecal microRNA stability in healthy cats

Lyngby, Janne Graarup, Kristensen, Annemarie T., Fredholm, Merete, Nielsen, Lise Nikolic & Cirera, Susanna, 2019, In: Veterinary Clinical Pathology. 48, 3, p. 455-460 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite-host cross talk

Hansen, E. P., Fromm, B., Andersen, S. D., Marcilla, A., Andersen, K. L., Borup, A., Williams, Andrew Richard, Jex, A. R., Gasser, R. B., Young, N. D., Hall, R. S., Stensballe, A., Ovchinnikov, V., Yan, Y., Fredholm, Merete, Thamsborg, Stig Milan & Nejsum, P., 2019, In: Journal of Extracellular Vesicles. 8, 1, 14 p., 1578116.

Research output: Contribution to journal › Journal article › Research › peer-review

Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

Ameen, C., Feuerborn, T. R., Brown, S. K., Linderholm, A., Hulme-Beaman, A., Lebrasseur, O., Sinding, M-H. S., Lounsberry, Z. T., Lin, A. T., Appelt, M., Bachmann, L., Betts, M., Britton, K., Darwent, J., Dietz, R., Fredholm, M., Gopalakrishnan, S., Goriunova, O. I., Grønnow, B., Haile, J. & 39 others, Hallsson, J. H., Harrison, R., Heide-Jørgensen, M. P., Knecht, R., Losey, R. J., Masson-MacLean, E., McGovern, T. H., McManus-Fry, E., Meldgaard, Morten, Midtdal, Å., Moss, M. L., Nikitin, I. G., Nomokonova, T., Pálsdóttir, A. H., Perri, A., Popov, A. N., Rankin, L., Reuther, J. D., Sablin, M., Schmidt, A. L., Shirar, S., Smiarowski, K., Sonne, C., Stiner, M. C., Vasyukov, M., West, C. F., Ween, G. B., Wennerberg, S. E., Wiig, Ø., Woollett, J., Dalén, L., Hansen, Anders Johannes, Gilbert, M Thomas P, Sacks, B. N., Frantz, L., Larson, G., Dobney, K., Darwent, C. M. & Evin, A., 2019, In: Proceedings. Biological sciences. 286, 1916, p. 20191929

Research output: Contribution to journal › Journal article › Research › peer-review

Kamphund eller ej?

Fredholm, Merete & Sandøe, Peter, 23 Feb 2018, In: Weekendavisen: Ideer. p. 4-5 2 p.

Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication

Ascaris suum infection down-regulates inflammatory pathways in the pig intestine in vivo and in human dendritic cells in vitro

Midttun, H. L. E., Acevedo, N., Skallerup, P., Almeida, Sara dos Santos, Skovgaard, K., Andresen, Lars, Skov, Søren, Caraballo, L., van Die, I., Jørgensen, Claus Bøttcher, Fredholm, Merete, Thamsborg, Stig Milan, Nejsum, P. & Williams, Andrew Richard, 2018, In: The Journal of Infectious Diseases. 217, 2, p. 310-319

Research output: Contribution to journal › Journal article › Research › peer-review

A targeted genotyping approach enhances identification of variants in taste receptor and appetite/reward genes of potential functional importance for obesity-related porcine traits

Cirera, Susanna, Clop, A., Jacobsen, M. J., Guerin, M., Lesnik, P., Jørgensen, Claus Bøttcher, Fredholm, Merete & Karlskov-Mortensen, Peter, 2018, In: Animal Genetics. 49, 2, p. 110–118

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of porcine body size variation using re-sequencing data of miniature and large pigs 06 Biological Sciences 0604 Genetics

Reimer, C., Rubin, C. J., Sharifi, A. R., Ha, N. T., Weigend, S., Waldmann, K. H., Distl, O., Pant, S. D., Fredholm, Merete, Schlather, M. & Simianer, H., 2018, In: BMC Genomics. 19, 17 p., 687.

Research output: Contribution to journal › Journal article › Research › peer-review

Brug af DNA-markører: til at bestemme, om en hund tilhører en forbudt race

Fredholm, Merete, Pedersen, L., Laursen, M. G. & Sandøe, Peter, 2018, In: Dansk Veterinaertidsskrift. 3, p. 26-28/ 3 p.

Research output: Contribution to journal › Journal article › Research

Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs

Mentzel, Caroline M. Junker, Cardoso, T. F., Pipper, C. B., Jacobsen, M. J., Jørgensen, Claus Bøttcher, Cirera, Susanna & Fredholm, Merete, 2018, In: Molecular Genetics and Genomics. 293, 1, p. 129–136 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Early microbial colonization affects DNA methylation of genes related to intestinal immunity and metabolism in preterm pigs

Pan, X., Gong, D., Nguyen, Duc Ninh, Zhang, X., Hu, Q., Lu, H., Fredholm, Merete, Sangild, Per Torp & Gao, Fei, 2018, In: D N A Research. 25, 3, p. 287–296

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of the mutation causing progressive retinal atrophy in Old Danish Pointing Dog

Karlskov-Mortensen, Peter, Proschowsky, Helle Friis, Gao, Fei & Fredholm, Merete, 2018, In: Animal Genetics. 49, 3, p. 237-241 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Interbreed variation in serum serotonin (5-hydroxytryptamine) concentration in updates healthy dogs

Hoglund, K., Haggstrom, J., Hanås, S., Merveille, A. -., Gouni, V., Wiberg, M., Willesen, Jakob, Mc Entee, K., Sorensen, L. M., Tiret, L., Seppala, E. H., Lohi, H., Chetboul, V., Fredholm, Merete, Lequarre, A. -. & Ljungvall, I., 2018, In: Journal of Veterinary Cardiology. 20, 4, p. 244-253

Research output: Contribution to journal › Journal article › Research › peer-review

Interbreed variation of biomarkers of lipid and glucose metabolism in dogs

Gomez-fernandez-blanco, C., Peeters, D., Moyse, E., Farnir, F., Höglund, K., Gouni, V., Wiberg, M., Lundgren Willesen, J., Hanås, S., Mcentee, K., Tiret, L., Häggström, J., Lohi, H., Chetboul, V., Fredholm, Merete, Seppälä, E. H., Lequarré, A. & Merveille, A., 2018, In: Veterinary Clinical Pathology. 47, 4, p. 582-588

Research output: Contribution to journal › Journal article › Research › peer-review

Circulating let-7g is down-regulated in Bernese Mountain dogs with disseminated histiocytic sarcoma and carcinomas: a prospective study

Børresen, Betina, Nielsen, Lise Nikolic, Jessen, Lisbeth Rem, Kristensen, Annemarie T., Fredholm, Merete & Cirera, Susanna, Jun 2017, In: Veterinary and Comparative Oncology. 15, 2, p. 525–533 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Transcriptional immune response in mesenteric lymph nodes in pigs with different levels of resistance to Ascaris suum

Skallerup, P., Nejsum, P., Cirera, Susanna, Skovgaard, K., Pipper, C. B., Fredholm, Merete, Jørgensen, Claus Bøttcher & Thamsborg, Stig Milan, Mar 2017, In: Acta Parasitologica. 62, 1, p. 141-153 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dyrevelfærdsmæssige problemer i forbindelse med hundeavl

Fredholm, Merete, 2017, In: Dansk Veterinaertidsskrift. 100, 6, p. 6-9

Research output: Contribution to journal › Journal article › Research › peer-review

Dyrevelfærdsmæssige problemer i forbindelse med hundeavl

Fredholm, Merete, 2017, In: Norsk Veterinaer-Tidsskrift. 2017, 4, p. 236-239

Research output: Contribution to journal › Journal article › Research › peer-review

FEELnc: A tool for long non-coding RNA annotation and its application to the dog transcriptome

Wucher, V., Legeai, F., Hédan, B., Rizk, G., Lagoutte, L., Leeb, T., Jagannathan, V., Cadieu, E., David, A., Lohi, H., Cirera Salicio, S., Fredholm, M., Botherel, N., Leegwater, P. A. J., Le Béguec, C., Fieten, H., Johnson, J. J., Alföldi, J., André, C., Lindblad-Toh, K. & 2 others, Hitte, C. & Derrien, T., 2017, In: Nucleic Acids Research. 45, 8, 12 p., e57.

Research output: Contribution to journal › Journal article › Research › peer-review

Fat and carbohydrate content in the diet induces drastic changes in gene expression in young Göttingen minipigs

Mentzel, Caroline M. Junker, Figueiredo Cardoso, T., Haagensen, A. M. J., Sørensen, Dorte Bratbo, Fredholm, Merete & Cirera, Susanna, 2017, In: Mammalian Genome. 28, 5-6, p. 166-175 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Haplotypes on pig chromosome 3 distinguish metabolically healthy from unhealthy obese individuals

Frederiksen, S. D., Karlskov-Mortensen, Peter, Pant, S. D., Guerin, M., Lesnik, P., Jørgensen, Claus Bøttcher, Cirera, Susanna, Bruun, Camilla Vibeke Sichlau, Mark, T. & Fredholm, Merete, 2017, In: PLoS ONE. 12, 6, 13 p., e0178828.

Research output: Contribution to journal › Journal article › Research › peer-review

Re-emergence of hereditary polyneuropathy in scandinavian alaskan malamute dogs-old enemy or new entity? A case series

Jäderlund, K. H., Rohdin, C., Berendt, Mette, Stigen, Ø., Fredholm, Merete, Espenes, A., Bjerkås, I. & Moe, L., 2017, In: Acta Veterinaria Scandinavica. 59, 1, 4 p., 26.

Research output: Contribution to journal › Journal article › Research › peer-review

Joint profiling of miRNAs and mRNAs reveals miRNA mediated gene regulation in the Göttingen minipig obesity model

Mentzel, Caroline M. Junker, Alkan, F., Keinicke, H., Jacobsen, M. J., Gorodkin, Jan, Fredholm, Merete & Cirera, Susanna, 30 Nov 2016, In: P L o S One. 11, 11, 16 p., e0167285.

Research output: Contribution to journal › Journal article › Research › peer-review

Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs

Jacobsen, M. J., Havgaard, Jakob Hull, Mentzel, Caroline M. Junker, Sørensen, P. M., Pundhir, Sachin, Anthon, Christian, Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Jørgensen, Claus Bøttcher, Barrès, Romain & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement 4, p. 46-47 2 p., P2019.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Focus on atherosclerosis and the pig as a model to identify genes affecting cholesterol and other plasma lipid levels.

Karlskov-Mortensen, Peter, Frederiksen, S. D., Pant, S. D., Cirera, Susanna, Jørgensen, Claus Bøttcher, Bruun, Camilla Vibeke Sichlau, Mark, T. & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement4, p. 152-152 1 p., P6009.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Differential Analysis of the Nasal Microbiome of Pig Carriers or Non-Carriers of Staphylococcus aureus

Espinosa-Gongora, C., Larsen, N., Schønning, Kristian, Fredholm, Merete & Guardabassi, Luca, 10 Aug 2016, In: P L o S One. 11, 8, 13 p., 0160331.

Research output: Contribution to journal › Journal article › Research › peer-review

Hepatic expression of inflammatory genes and microRNAs in pigs with high "cholesteryl ester transfer protein" (CETP) activity

Cirera, Susanna, Tørsleff, B. C. J., Ritz, C., Fredholm, Merete, Heegaard, P. M. H. & Skovgaard, K., 30 May 2016, In: Mammalian Genome. 27, 9, p. 503-510 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A large insertion in intron 2 of the TYRP1 gene associated with American Palomino phenotype in American mink

Cirera, Susanna, Markakis, M. N., Kristensen, Thea, Vissenberg, K., Fredholm, Merete, Christensen, Knud Arnbjerg & Anistoroaei, R. M., Apr 2016, In: Mammalian Genome. 27, 3, p. 135-143 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of breed on plasma endothelin-1 concentration, plasma renin activity, and serum cortisol concentration in healthy dogs

Höglund, K., Lequarré, A., Ljungvall, I., Mc Entee, K., Merveille, A., Wiberg, M., Gouni, V., Willesen, Jakob, Hanås, S., Wess, G., Mejer Sørensen, L., Tiret, L., Kierczak, M., Forsberg, S. K. G., Seppälä, E., Lindblad-Toh, K., Lohi, H., Chetboul, V., Fredholm, Merete & Häggström, J., Mar 2016, In: Journal of Veterinary Internal Medicine. 30, 2, p. 566-573 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Discrepancy in compliance between the clinical and genetic diagnosis of choroidal hypoplasia in Danish Rough Collies and Shetland Sheepdogs

Fredholm, Merete, Larsen, R. C., Jönsson, M., Söderlund, M. A., Hardon, T. & Proschowsky, Helle Friis, 6 Jan 2016, In: Animal Genetics. 47, 2, p. 250-252 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity

Jacobsen, M. J., Mentzel, Caroline M. Junker, Olesen, A. S., Huby, T., Jørgensen, Claus Bøttcher, Barrès, Romain, Fredholm, Merete & Simar, D., 2016, In: Journal of Diabetes Research. 2016, p. 1-11 8539057.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of protein-damaging mutations in 10 swine taste receptors and 191 appetite-reward genes

Clop, A., Sharaf, A., Castelló, A., Ramos-Onsins, S., Cirera, Susanna, Mercadé, A., Derdak, S., Beltran, S., Huisman, A., Fredholm, Merete, van As, P. & Sánchez, A., 2016, In: BMC Genomics. 17, 17 p., 685.

Research output: Contribution to journal › Journal article › Research › peer-review

Physical training and weight loss in dogs lead to transcriptional changes in genes involved in the glucose-transport pathway in muscle and adipose tissues

Herrera Uribe, J., Vitger, Anne Désiré, Ritz, C., Fredholm, Merete, Bjørnvad, Charlotte Reinhard & Cirera, Susanna, 2016, In: The Veterinary Journal. 208, p. 22-27 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The prevalence of the electrocardiographic J wave in the Petit Basset Griffon Vendéen compared to 10 different dog breeds

Rudling, E. H., Schlamowitz, S., Pipper, C. B., Nilsson, E., Höllmer, M., Willesen, Jakob, Berendt, Mette, Fredholm, Merete, Gulløv, C. H., Christiansen, M. & Koch, Jørgen, 2016, In: Journal of Veterinary Cardiology. 18, 1, p. 26-33 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Expression study of GLUT4 translocation-related genes in a porcine pre-diabetic model

Kristensen, Thea, Fredholm, Merete & Cirera, Susanna, Dec 2015, In: Mammalian Genome. 26, 11, p. 650-657 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

An integrative systems genetics approach reveals potential causal genes and pathways related to obesity

Kogelman, L., Zhernakova, D. V., Westra, H., Cirera, Susanna, Fredholm, Merete, Franke, L. & Kadarmideen, H., 20 Oct 2015, In: Genome Medicine. 7, 15 p., 105.

Research output: Contribution to journal › Journal article › Research › peer-review

Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans

Pant, S. D., Karlskov-Mortensen, Peter, Jacobsen, M. J., Cirera, Susanna, Kogelman, L., Bruun, Camilla Vibeke Sichlau, Mark, T., Jørgensen, Claus Bøttcher, Grarup, Niels, Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, Oluf Borbye, Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 8 Sep 2015, In: PLOS ONE. 10, 9, 22 p., e0137356.

Research output: Contribution to journal › Journal article › Research › peer-review

Prevalence and heritability of distichiasis in the English Cocker spaniel

Petersen, T., Proschowsky, Helle Friis, Hardon, T., Nyhuus Rasch, S. & Fredholm, Merete, 2 Aug 2015, In: Canine Genetics and Epidemiology. 2, 6 p., 11.

Research output: Contribution to journal › Journal article › Research › peer-review

Gender and obesity specific MicroRNA expression in adipose tissue from lean and obese pigs

Mentzel, Caroline M. Junker, Anthon, Christian, Jacobsen, M. J., Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Jørgensen, Claus Bøttcher, Gorodkin, Jan, Cirera, Susanna & Fredholm, Merete, 29 Jul 2015, In: P L o S One. 10, 7, 19 p., e0131650.

Research output: Contribution to journal › Journal article › Research › peer-review

Detection of a quantitative trait locus associated with resistance to infection with Trichuris suis in pigs

Skallerup, P., Thamsborg, Stig Milan, Jørgensen, Claus Bøttcher, Mejer, Helena, Göring, H. H. H., Archibald, A. L., Fredholm, Merete & Nejsum, P., 2015, In: Veterinary Parasitology. 210, 3-4, p. 264-269 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study reveals a locus for nasal carriage of Staphylococcus aureus in Danish crossbred pigs

Skallerup, P., Gongora, C. E., Jørgensen, Claus Bøttcher, Guardabassi, Luca & Fredholm, Merete, 2015, In: B M C Veterinary Research. 11, 8 p., 290.

Research output: Contribution to journal › Journal article › Research › peer-review

Prevalence and heritability of symptomatic syringomyelia in Cavalier King Charles Spaniels and long-term outcome in symptomatic and asymptomatic littermates

Thøfner, M. S., Stougaard, C. L., Westrup, U., Madry, A. A., Knudsen, C. S., Berg, H., Jensen, C. S. E., Handby, R. M. L., Gredal, Hanne Birgit, Fredholm, Merete & Berendt, Mette, 2015, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 29, 1, p. 243-250 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The shepherds' tale: a genome-wide study across 9 dog breeds implicates two loci in the regulation of fructosamine serum concentration in Belgian shepherds

Forsberg, S. K. G., Kierczak, M., Ljungvall, I., Merveille, A-C., Gouni, V., Wiberg, M., Willesen, J., Hanås, S., Lequarré, A-S., Mejer Sørensen, L., Tiret, L., McEntee, K., Seppälä, E., Koch, J., Battaille, G., Lohi, H., Fredholm, M., Chetboul, V., Häggström, J., Carlborg, Ö. & 2 others, Lindblad-Toh, K. & Höglund, K., 2015, In: PLOS ONE. 10, 5, 17 p., e0123173.

Research output: Contribution to journal › Journal article › Research › peer-review

A hereditary disposition for bovine peripheral nerve sheath tumors in Danish Holstein cattle

Grossi, A. B., Agerholm, Jørgen Steen, Christensen, Knud Arnbjerg, Jensen, Henrik Elvang, Leifsson, Páll S., Bendixen, C., Karlskov-Mortensen, Peter & Fredholm, Merete, 2014, In: Acta Veterinaria Scandinavica (Online). 56, 6 p., 85.

Research output: Contribution to journal › Journal article › Research › peer-review

Breed differences in natriuretic peptides in healthy dogs

Sjöstrand, K., Wess, G., Ljungvall, I., Häggström, J., Merveille, A-C., Wiberg, M., Gouni, V., Willesen, J., Hanås, S., Lequarré, A-S., Sørensen, L. M., Wolf, J., Tiret, L., Kierczak, M., Forsberg, S., McEntee, K., Battaille, G., Seppälä, E., Lindblad-Toh, K., Georges, M. & 4 others, Lohi, H., Chetboul, V., Fredholm, Merete & Höglund, K., 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 451-457 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Clinical findings and prevalence of the mutation associated with Primary ciliary dyskinesia in Old English Sheepdogs

Merveille, A., Battaille, G., Billen, F., Deleuze, S., Fredholm, Merete, Thomas, A., Clercx, C. & Lequarre, A., 2014, In: Journal of Veterinary Internal Medicine. 28, 3, p. 771-778 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Expression studies of six human obesity-related genes in seven tissues from divergent pig breeds

Cirera, Susanna, Jensen, M. S., Elbrønd, V. S., Moesgaard, S. G., Christoffersen, B. O., Kadarmideen, H., Skovgaard, K., Bruun, Camilla Vibeke Sichlau, Karlskov-Mortensen, Peter, Jørgensen, Claus Bøttcher & Fredholm, Merete, 2014, In: Animal Genetics. 45, 1, p. 59-66 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Functional study of a genetic marker allele associated with resistance to Ascaris suum in pigs

Skallerup, P., Thamsborg, Stig Milan, Jørgensen, Claus Bøttcher, Enemark, H. L., Yoshida, A., Göring, H. H., Fredholm, Merete & Nejsum, P., 2014, In: Parasitology. 141, 6, p. 777-787 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine model

Kogelman, L., Cirera, Susanna, Zhernakova, D. V., Fredholm, Merete, Franke, L. & Kadarmideen, H., 2014, In: B M C Genomics. 7, 16 p., 57.

Research output: Contribution to journal › Journal article › Research › peer-review

Identifying QTL and genetic correlations between fur quality traits in mink (Neovison vison)

Thirstrup, J. P., Anistoroaei, R. M., Guldbrandtsen, B., Christensen, Knud Arnbjerg, Fredholm, Merete & Nielsen, V. H., 2014, In: Animal Genetics. 45, 1, p. 105-110 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Perosomus elumbis in Danish Holstein cattle

Agerholm, Jørgen Steen, Holm, W., Schmidt, M., Hyttel, P., Fredholm, Merete & McEvoy, Fintan, 2014, In: B M C Veterinary Research. 10, 6 p., 227.

Research output: Contribution to journal › Journal article › Research › peer-review

Structured RNAs and synteny regions in the pig genome

Anthon, Christian, Tafer, H., Havgaard, Jakob Hull, Thomsen, B., Hedegaard, J., Seemann, Ernst Stefan, Pundhir, Sachin, Kehr, S., Bartschat, S., Nielsen, M., Nielsen, R. O., Fredholm, Merete, Stadler, P. F. & Gorodkin, Jan, 2014, In: BMC Genomics. 15, 27 p., 459.

Research output: Contribution to journal › Journal article › Research › peer-review

Systems genetics of obesity in an F2 pig model by genome-wide association, genetic network and pathway analyses

Kogelman, L., Pant, S. D., Fredholm, Merete & Kadarmideen, H., 2014, In: Frontiers in Genetics. 5, 15 p., 214.

Research output: Contribution to journal › Journal article › Research › peer-review

Vad är fel med min bulldogg? att förebygga avel av hundar med brakycefalt syndrom

Sandøe, Peter, Hansen, I. K., Göransson, M., Eriksen, Thomas & Fredholm, Merete, 2014, In: Svensk Veterinaertidning. 2014, 8-9, p. 23-27 5 p.

Research output: Contribution to journal › Journal article › Research

A Gly98Val mutation in the N-myc downstream regulated gene 1 (NDRG1) in Alaskan Malamutes with polyneuropathy

Bruun, C. V. S., Jäderlund, K. H., Berendt, M., Jensen, K. B., Spodsberg, E-M. H., Gredal, H. B., Shelton, G. D., Mickelson, J. R., Minor, K. M., Lohi, H., Bjerkås, I., Stigen, Ø., Espenes, A., Rohdin, C., Edlund, R., Ohlsson, J., Cizinauskas, S., Leifsson, P. S., Drögemüller, C., Moe, L. & 2 others, Cirera, Susanna & Fredholm, Merete, 2013, In: PLOS one. 8, 2, p. 1-7 7 p., e54547.

Research output: Contribution to journal › Journal article › Research › peer-review

An F2 pig resource population as a model for genetic studies of obesity and obesity-related diseases in humans: design and genetic parameters

Kogelman, L., Kadarmideen, H., Mark, T., Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Jacobsen, M. J., Jørgensen, Claus Bøttcher & Fredholm, Merete, 2013, In: Frontiers in Genetics. 4, 14 p., 29.

Research output: Contribution to journal › Journal article › Research › peer-review

Characterization of the genetic profile of five Danish dog breeds

Pertoldi, C., Kristensen, T. N., Loeschcke, V., Berg, P., Praebel, A., Stronen, A. V., Proschowsky, Helle Friis & Fredholm, Merete, 2013, In: Journal of Animal Science. 91, 11, p. 5122-5127 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Functional characterization of a porcine emphysema model

Bruun, Camilla Vibeke Sichlau, Jensen, Louise Kruse, Leifsson, Páll S., Nielsen, J., Cirera, Susanna, Jørgensen, Claus Bøttcher, Jensen, Henrik Elvang & Fredholm, Merete, 2013, In: Lung. 191, 6, p. 669-675 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Hvad er der galt med min bulldog? om mulighederne for at forebygge fremavl af hunde med brachycephalt syndrom

Sandøe, Peter, Hansen, I. K., Eriksen, Thomas & Fredholm, Merete, 2013, In: Dansk Veterinærtidsskrift. 96, 12, p. 11-14 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Ichthyosis hos golden retriever i Danmark

Berg, J., Boysen, L., Fredholm, Merete & Proschowsky, Helle Friis, 2013, In: Dansk Veterinaertidsskrift. 96, 7, p. 12-14 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Potential role of the porcine superoxide dismutase 1 (SOD1) gene in pig reproduction

Bjerre, D., Madsen, L. B., Mark, T., Cirera, Susanna, Larsen, K., Jørgensen, Claus Bøttcher & Fredholm, Merete, 2013, In: Animal Biotechnology (Print Edition). 24, 1, p. 1-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Profiling microRNAs in lung tissue from pigs infected with Actinobacillus pleuropneumoniae

Podolska, A., Anthon, Christian, Bak, M., Tommerup, Niels, Skovgaard, K., Heegaard, P. M., Gorodkin, Jan, Cirera, S. & Fredholm, Merete, Sep 2012, In: B M C Genomics. 13, 1, p. 459

Research output: Contribution to journal › Journal article › Research › peer-review

A deletion in the bovine FANCI gene compromises fertility by causing fetal death and brachyspina

Charlier, C., Agerholm, Jørgen Steen, Coppieters, W., Karlskov-Mortensen, Peter, Li, W., Jong, G. D., Fasquelle, C., Karim, L., Cirera, Susanna, Gambisano, N., Ahariz, N., Mullaart, E., Georges, M. & Fredholm, Merete, 2012, In: PLoS ONE. 7, 8, 7 p., e43085.

Research output: Contribution to journal › Journal article › Research › peer-review

A molecular study of congenital erythropoietic porphyria in cattle

Agerholm, Jørgen Steen, Thulstrup, Peter Waaben, Bjerrum, Morten Jannik, Bendixen, C., Jørgensen, Claus Bøttcher & Fredholm, Merete, 2012, In: Animal Genetics. 43, 2, p. 210-215 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A re-assigned American mink (Neovison vison) map optimal for genome-wide studies

Anistoroaei, R. M., Nielsen, V. H., Markakis, M. N., Karlskov-Mortensen, Peter, Jørgensen, Claus Bøttcher, Christensen, Knud Arnbjerg & Fredholm, Merete, 2012, In: Gene. 511, 1, p. 66-72 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Analyses of pig genomes provide insight into porcine demography and evolution

Groenen, M. A., Archibald, A. L., Uenishi, H., Tuggle, C. K., Takeuchi, Y., Rothschild, M. F., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H-J., Li, S., Larkin, D. M., Kim, H., Frantz, L. A. F., Caccamo, M., Ahn, H., Aken, B. L., Anselmo, A., Anthon, C., Auvil, L. & 116 others, Badaoui, B., Beattie, C. W., Bendixen, C., Berman, D., Blecha, F., Blomberg, J., Bolund, L., Bosse, M., Botti, S., Zhan, B., Bystrom, M., Capitanu, B., Carvalho-Silva, D., Chardon, P., Chen, C., Cheng, R., Choi, S., Chow, W., Clark, R. C., Clee, C., Crooijmans, R. P. M. A., Dawson, H. D., Dehais, P., Sapio, F. D., Dibbits, B., Drou, N., Du, Z., Eversole, K., Fadista, J., Fairley, S., Faraut, T., Faulkner, G. J., Fowler, K. E., Fredholm, Merete, Fritz, E., Gilbert, J. G. R., Giuffra, E., Gorodkin, Jan, Griffin, D. K., Harrow, J. L., Hayward, A., Howe, K., Hu, Z., Humphray, S. J., Hunt, T., Jensen, H. H., Jeon, J., Jern, P., Jones, M., Jurka, J., Kanamori, H., Kapetanovic, R., Kim, J., Kim, J., Kim, K., Kim, T., Larson, G., Lee, K., Lee, K., Leggett, R., Lewin, H. A., Li, Y., Liu, W., Loveland, J. E., Lu, Y., Lunney, J. K., Ma, J., Madsen, O., Mann, K., Matthews, L., McLaren, S., Morozumi, T., Murtaugh, M. P., Narayan, J., Nguyen, D. T., Ni, P., Oh, S., Onteru, S., Panitz, F., Park, E., Park, H., Pascal, G., Paudel, Y., Perez-Enciso, M., Ramirez-Gonzalez, R., Reecy, J. M., Rodriguez-Zas, S., Rohrer, G. A., Rund, L., Sang, Y., Schachtschneider, K., Schraiber, J. G., Schwartz, J., Scobie, L., Scott, C., Searle, S., Servin, B., Southey, B. R., Sperber, G., Stadler, P., Sweedler, J. V., Tafer, H., Thomsen, B., Wali, R., Wang, J., Wang, J., White, S., Xu, X., Yerke, M., Zhang, G., Zhang, J., Zhang, J., Zhao, S., Rogers, J., Churcher, C. & Schook, L. B., 2012, In: Nature. 491, 7424, p. 393-398 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Detection of a quantitative trait locus associated with resistance to Ascaris suum infection in pigs

Skallerup, P., Nejsum, P., Jørgensen, Claus Bøttcher, Göring, H. H. H., Karlskov-Mortensen, Peter, Archibald, A. L., Fredholm, Merete & Thamsborg, Stig Milan, 2012, In: International Journal for Parasitology. 42, 4, p. 383-391 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Expression of matrix metalloproteinase-9 and -12 in porcine lung infections

Bruun, Camilla Vibeke Sichlau, Leifsson, Páll S., Jensen, Louise Kruse, Jensen, Henrik Elvang, Nielsen, J. & Fredholm, Merete, 2012, In: Journal of Comparative Pathology. 146, 2-3, p. 253-257 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of a novel idiopathic epilepsy locus in Belgian Shepherd dogs

Seppälä, E. H., Koskinen, L. L. E., Gulløv, C. H., Jokinen, P., Karlskov-Mortensen, Peter, Bergamasco, L., Körberg, I. B., Cizinauskas, S., Oberbauer, A. M., Berendt, Mette, Fredholm, Merete & Lohi, H., 2012, In: P L o S One. 7, 3, 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Rethinking dog domestication by integrating genetics, archeology, and biogeography

Larson, G., Karlsson, E. K., Perri, A., Webster, M. T., Ho, S. Y. W., Peters, J., Stahl, P. W., Piper, P. J., Lingaas, F., Fredholm, Merete, Comstock, K. E., Modiano, J. F., Schelling, C., Agoulnik, A. I., Leegwater, P. A., Dobney, K., Vigne, J., Vilà, C., Andersson, L. & Lindblad-Toh, K., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 23, p. 8878-8883 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Selective inbreeding does not increase gut microbiota similarity in BALB/c mice

Pang, W., Stradiotto, D., Krych, Lukasz, Karlskov-Mortensen, Peter, Vogensen, Finn Kvist, Nielsen, Dennis Sandris, Fredholm, Merete & Hansen, Axel Kornerup, 2012, In: Laboratory Animals. 46, 4, p. 335-337 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Strong signatures of selection in the domestic pig genome

Rubin, C., Megens, H., Barrio, A. M., Maqbool, K., Sayyab, S., Schwochow, D., Wang, C., Carlborg, Ö., Jern, P., Jørgensen, Claus Bøttcher, Archibald, A. L., Fredholm, Merete, Groenen, M. A. M. & Andersson, L., 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 48, p. 19529-36 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Validation of genome-wide intervertebral disk calcification associations in Dachshund and further investigation of the chromosome 12 susceptibility locus

Ryt-Hansen, M. E., Scheibye-Alsing, K., Karlskov-Mortensen, Peter, Proschowsky, Helle Friis, Jensen, V. F., Bak, M., Tommerup, Niels, Kadarmideen, H. & Fredholm, Merete, 2012, In: Frontiers in Genetics. 3, 225, 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Characterisation of five candidate genes within the ETEC F4ab/ac candidate region in pigs

Jacobsen, M. J., Cirera, Susanna, Joller, D., Esteso, G., Kracht, S. S., Edfors, I., Bendixen, C., Archibald, A. L., Vogeli, P., Neuenschwander, S., Bertschinger, H. U., Rampoldi, A., Andersson, L., Fredholm, Merete & Jørgensen, Claus Bøttcher, 2011, In: BMC Research Notes. 4, 225, 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Exonization of a LINE1 fragment implicated in X-linked hypohidrotic ectodermal dysplasia in cattle

Karlskov-Mortensen, Peter, Cirera, Susanna, Nielsen, O. L., Arnbjerg, J., Reibel, Jesper, Fredholm, Merete & Agerholm, Jørgen Steen, 2011, In: Animal Genetics. 42, 6, p. 578-584 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study in Dachshund: identification of a major locus affecting intervertebral disc calcification

Mogensen, M. S., Karlskov-Mortensen, Peter, Proschowsky, Helle Friis, Lingaas, F., Lappalainen, A., Lohi, H., Jensen, V. F. & Fredholm, Merete, 2011, In: Journal of Heredity. 102, Suppl. 1, p. S81-S86 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

How the RNA isolation method can affect microRNA microarray results

Podolska, A., Kaczkowski, B., Litman, Thomas, Fredholm, Merete & Cirera, Susanna, 2011, In: Acta Biochimica Polonica. 58, 4, p. 535-540 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of 2 loci associated with development of myxomatous mitral valve disease in Cavalier King Charles Spaniels

Madsen, M. B., Olsen, Lisbeth Høier, Häggström, J., Höglund, K., Ljungvall, I., Falk, B. T., Wess, G., Stephenson, H., Dukes-McEwan, J., Chetboul, V., Gouni, V., Proschowsky, Helle Friis, Cirera, Susanna, Karlskov-Mortensen, Peter & Fredholm, Merete, 2011, In: Journal of Heredity. 102, Suppl. 1, p. S62-S67 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping

Vaysse, A., Ratnakumar, A., Derrien, T., Axelsson, E., Pielberg, G. R., Sigurdsson, S., Fall, T., Seppälä, E. H., Hansen, M. S. T., Lawley, C. T., Karlsson, E. K., Bannasch, D., Vilà, C., Lohi, H., Galibert, F., Fredholm, M., Häggström, J., Hedhammar, Å., André, C., Lindblad-Toh, K. & 2 others, Hitte, C. & Webster, M. T., 2011, In: PLoS Genetics. 7, 10, 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

LUPA: a European initiative taking advantage of the canine genome architecture for unravelling complex disorders in both human and dogs

Lequarré, A., Andersson, L., André, C., Fredholm, Merete, Hitte, C., Leeb, T., Lohi, H., Lindblad-Toh, K. & Georges, M., 2011, In: The Veterinary Journal. 189, 2, p. 155-159 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

MicroRNA expression profiling of the porcine developing brain

Podolska, A., Kaczkowski, B., Busk, P. K., Søkilde, R., Litman, T., Fredholm, Merete & Cirera, Susanna, 2011, In: P L o S One. 6, p. e14494 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The receptor locus for escherichia coli F4ab/F4ac in the pig maps distal to the MUC4-LMLN region

Rampoldi, A., Jacobsen, M. J., Bertschinger, H. U., Joller, D., Bürgi, E., Vögeli, P., Andersson, L., Archibald, A. L., Fredholm, Merete, Jørgensen, Claus Bøttcher & Neuenschwander, S., 2011, In: Mammalian Genome. 22, 1-2, p. 122-129 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A study of alternative splicing in the pig

Hillig, A. N., Cirera, Susanna, Gilchrist, M. J., Gorodkin, Jan, Jørgensen, Claus Bøttcher & Fredholm, Merete, 2010, In: BMC Research Notes. 3, 123, 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Expression profiles of miRNA-122 and its target CAT1 in minipigs (Sus scrofa) fed a high-cholesterol diet

Cirera, Susanna, Birck, M. M., Busk, P. K. & Fredholm, Merete, 2010, In: Comparative Medicine. 60, 2, p. 136-141 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Expression studies of the obesity candidate gene FTO in pig

Madsen, M. B., Birck, M. M., Fredholm, Merete & Cirera, Susanna, 2010, In: Animal Biotechnology (Print Edition). 21, 1, p. 51-63 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

First confirmed case of the bovine brachyspina syndrome in Canada

Agerholm, Jørgen Steen, DeLay, J., Hicks, B. & Fredholm, Merete, 2010, In: Canadian Veterinary Journal. 51, p. 1349-1350 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Investigation of candidate regions influencing litter size in Danish Landrace sows

Bjerre, D., Mark, T., Sørensen, P., Proschowsky, Helle Friis, Vernersen, A., Jørgensen, Claus Bøttcher & Fredholm, Merete, 2010, In: Journal of Animal Science. 88, 5, p. 1603-1609 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Investigation of tissue-specific human orthologous alternative splice events in pig

Hillig, A. N., Jørgensen, Claus Bøttcher, Cirera, Susanna & Fredholm, Merete, 2010, In: Animal Biotechnology (Print Edition). 21, 4, p. 203-216 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Pig genome sequence - analysis and publication strategy

Archibald, A. L., Bolund, L., Churcher, C., Fredholm, Merete, Groenen, M. A. M., Harlizius, B., Lee, K., Milan, D., Rogers, J., Rothschild, M. F., Uenishi, H., Wang, J. & Schook, L. B., 2010, In: BMC Genomics. 11, 438, 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The minipig as a platform for new technologies in toxicology

Forster, R., Ancian, P., Fredholm, Merete, Simianer, H. & Whitelaw, B., 2010, In: Journal of Pharmacological and Toxicological Methods. 62, 3, p. 227-235 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A study of the occurrence of monochorionic and monozygotic twinning in the pig

Bjerre, D., Thorup, F., Jørgensen, Claus Bøttcher, Vejlsted, M. & Fredholm, Merete, 2009, In: Animal Genetics. 40, 1, p. 53-56 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Focal epilepsy in the Belgian shepherd: evidence for simple Mendelian inheritance

Berendt, Mette, Gulløv, C. H. & Fredholm, Merete, 2009, In: Journal of Small Animal Practice. 50, 12, p. 655-661 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review